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Famotidine (H2 Receptor Antagonist)

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Famotidine (H2 Receptor Antagonist)

Famotidine (H2 Receptor Antagonist)

https://youtu.be/TtN0gwP16cc

MATH+ '+' protocol advocates the use of Famotidine based on the study showing reduction in the risk of intubation and death in COVID-19 patients.

Famotidine, sold under the brand name Pepcid among others, is a medication that decreases stomach acid production.[2] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome.[2] It is taken by mouth or by injection into a vein.[2] It begins working within an hour.[2]

Common side effects include headache, intestinal upset, and dizziness.[2] Serious side effects may include pneumonia and seizures.[2][3] Use in pregnancy appears safe but has not been well studied while use during breastfeeding is not recommended.[4] It is a histamine H2 receptor antagonist.[2]

Famotidine

https://en.wikipedia.org/wiki/Famotidine

Gastrin

https://en.wikipedia.org/wiki/Gastrin

Enterochromoaffin-like cells

https://en.wikipedia.org/wiki/Enterochromaffin-like_cell

In this lecture Dr. Mobeen will discuss:

1. The use of famotidine in MATH+ protocol. (00.40)

2. Different types of H2 blockers. (1:49)

3. Physiology of gastric acid secretion. (3:55)

4. Role of prostaglandin in gastric acid secretion and the adverse effect of non-steroidal anti-inflammatory drugs. (11:05)

5. Function of the vagus nerve in gastric acid secretion. (14:30)

6. Mechanism of action of famotidine. (15:12)

7. Pharmacokinetics and pharmacodynamics of famotidine. (18:37)

8. Uses and side effects of famotidine. (20:33)

9. Preprint observational study findings with the use of famotidine in COVID-19 patients. (21:00)

Presented by Dr. Mobeen Syed

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